
PLpro inhibitor
CAS No. 1093070-14-4
PLpro inhibitor( —— )
Catalog No. M22162 CAS No. 1093070-14-4
PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM).
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 174 | In Stock |
![]() ![]() |
5MG | 260 | In Stock |
![]() ![]() |
10MG | 372 | In Stock |
![]() ![]() |
25MG | 619 | In Stock |
![]() ![]() |
50MG | 881 | In Stock |
![]() ![]() |
100MG | 1188 | In Stock |
![]() ![]() |
500MG | 2367 | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NamePLpro inhibitor
-
NoteResearch use only, not for human use.
-
Brief DescriptionPLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM).
-
DescriptionPLpro inhibitor is a potent papain-like protease (PLpro) inhibitor(IC50 of 2.6 uM)
-
In VitroPLpro inhibitor is a potent inhibitor against the papain-like protease (PLpro) from the coronavirus that causes severe acute respiratory syndrome (SARS-CoV). PLpro inhibitor was found to have IC50 value of 2.6 μM. PLpro inhibitor display significant antiviral activity with EC50 values of 13.1 μM, without toxicity up to the highest concentration tested. Notably, the increasing antiviral potency correlates with the in vitro inhibition of PLpro, suggesting that the compounds work directly on the enzyme in cells.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptorpapain-like protease (PLpro)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1093070-14-4
-
Formula Weight346.42
-
Molecular FormulaC22H22N2O2
-
Purity>98% (HPLC)
-
SolubilityDMSO : 40 mg/mL (115.47 mM)
-
SMILESC[C@@H](NC(=O)c1cc(NC(C)=O)ccc1C)c1cccc2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ratia, K., et al., A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A, 2008. 105(42): p. 16119-24.
molnova catalog



related products
-
Tartrazine
Tartrazine is a food additive that belongs to a class of artificial dyes and contains an azo group.
-
S-Y048
S-Y048 is an Oxoeicosanoid (OXE) receptor antagonist that inhibits allergen-induced eosinophil infiltration into the skin of experimentally sensitized rhesus monkeys to house dust mites and inhibits lung inflammation caused by aerosolized allergen challenge.
-
Gerardianin D
The young shoots of Chamaecyparis obtusa.